Calcium gluconate 10%

Antidote for clinically significant magnesium toxicity

IV

Initial antidote dose; reassess breathing, ECG and calcium before further dosing

Emergency reversal; stop magnesium and support the airway concurrently · 10% = 100 mg/mL; 10 mL contains 1 g calcium gluconate, NOT 1 g elemental calcium. Give over at least 5 min through a patent IV line; do not mix with other drugs

No automatic repeated-dose course; further calcium requires monitored reassessment

Clinically important hypocalcaemia during major transfusion, guided by ionised calcium and physiology

IV

Initial dose followed by ionised-calcium/ECG reassessment; titrate further replacement to the monitored result

During the acute deficit and ongoing citrate exposure; stop/reduce when ionised calcium normalises · 10% = 100 mg/mL; 10 mL contains 1 g calcium gluconate, NOT 1 g elemental calcium. Give over at least 5 min through a patent IV line; do not mix with other drugs

No fixed every-four-units schedule: reassess calcium and prescribe further doses explicitly