ODOBGYNDECODED

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Cefalexin

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

CefalexinCephalosporin antibacterial

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Cefalexin: indication-specific regimens
IndicationDoseRouteFrequencyDuration / preparationMaximumMonitoring / cautions
NICE second-choice lower-UTI option when suitable for culture results/allergy history
500 mg
Oral
Twice daily
7 days · 500 mg capsule/tablet; swallow with water. If a suspension is used, verify its concentration and measure the prescribed mg
  • Dose adjustment is required with renal impairment. This is not the pyelonephritis step-down prescription for every organism.
1000 mg/day in this uncomplicated lower-UTI regimen; other infections have different schedules
Monitor
  • Culture/susceptibility, response within 48 hours, allergy, diarrhoea and renal function
Contraindications / cautions
  • Cephalosporin allergy; assess severe immediate beta-lactam allergy. Systemic/upper-UTI features need a different regimen
Pregnancy safety
Pregnancy lower-UTI option selected by culture/allergy context
Lactation
Monitor infant for GI effects or sensitisation
NICEcheckedIN REVIEW