ODOBGYNDECODED

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Clindamycin

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

ClindamycinEMERGENCY KITAntibiotics

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Clindamycin: indication-specific regimens
IndicationDoseRouteFrequencyDuration / preparationMaximumMonitoring / cautions
Postpartum endometritis, in combination with gentamicin when appropriate
900 mg
IV infusion
Every 8 hours
Continue until clinical improvement and afebrile for 24–48 h in the cited NAG regimen; persistent fever needs source reassessment · 150 mg/mL concentrate: 900 mg =6 mL; dilute in compatible IV fluid and infuse over at least 30 min (not IV push)
2700 mg/day in this regimen
Monitor
  • Temperature, uterine tenderness, renal function/gentamicin levels for the partner drug; diarrhoea/C. difficile risk
Contraindications / cautions
  • Clindamycin allergy; previous severe antibiotic-associated colitis requires assessment
Symptomatic bacterial vaginosis when an oral alternative is appropriate
300 mg
Oral
Twice daily
7 days · 300 mg capsule or two 150 mg capsules per dose; swallow with a full glass of water
  • Do not shorten this CDC pregnancy BV course to five days.
600 mg/day in this BV regimen, separate from 900 mg IV emergency dosing
Monitor
  • Symptom response, intolerance and severe/persistent diarrhoea suggestive of C. difficile
Contraindications / cautions
  • Clindamycin/lincomycin allergy; previous antibiotic-associated colitis needs careful assessment
Pregnancy safety
Use for an indicated infection with appropriate combination therapy.
Lactation
Acute maternal stabilisation takes priority; review ongoing treatment and infant exposure with the linked source and specialist team.