Erythromycin (latency PPROM)

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

Erythromycin (latency PPROM)Macrolide

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Erythromycin (latency PPROM): indication-specific regimens
Indication	Dose	Route	Frequency	Duration / preparation	Maximum	Monitoring / cautions
Confirmed PPROM without established infection or another indication for immediate birth NICE · NG25checked	250 mg	Oral	Four times daily	Maximum 10 days OR until established labour, whichever occurs first (NICE NG25) · 250 mg tablets; confirm the erythromycin salt and avoid erythromycin estolate in pregnancy. Do not substitute co-amoxiclav for latency prophylaxis	1 g/day for at most 10 days in this regimen	Monitor Temperature, pulse, uterine tenderness, fetal status and drug tolerance; infection changes management Contraindications / cautions Macrolide allergy; QT prolongation and interacting drugs; do not use latency antibiotics to defer delivery in sepsis

Pregnancy safety

GTG73 regimen

Lactation

Compatible