Hydralazine

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

HydralazineEMERGENCY KITDirect vasodilator

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Hydralazine: indication-specific regimens
Indication	Dose	Route	Frequency	Duration / preparation	Maximum	Monitoring / cautions
Alternative for acute severe hypertension MSFchecked	5 mg slowly IV over 2–4 min; reassess for 20 min and repeat 5 mg if still severe	IV	Every 20 min if required after reassessment	Acute control; transition to oral therapy once stable · Reconstitute a 20 mg vial with 1 mL water for injection, then add 9 mL sodium chloride 0.9%: 2 mg/mL. A 5 mg dose = 2.5 mL. Use immediately; do not mix with other drugs Renal / hepatic: Reduce doses with renal/hepatic impairment	20 mg cumulative in this MSF bolus regimen	Monitor Check BP and pulse before and after each acute dose; fetal monitoring when appropriate Persistent severe BP despite the initial sequence requires senior/anaesthetic review, a different agent and HDU-level monitoring; avoid uncontrolled stacking Contraindications / cautions Marked hypotension, severe tachycardia or coronary ischaemia; use cautiously in cardiac disease

Pregnancy safety

Established obstetric use

Lactation

Compatible

Adverse effects

Reflex tachycardia/headache/fluid retention