ODOBGYNDECODED

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Levonorgestrel ECP

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

Levonorgestrel ECPProgestogen EC

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Levonorgestrel ECP: indication-specific regimens
IndicationDoseRouteFrequencyDuration / preparationMaximumMonitoring / cautions
After unprotected/inadequately protected intercourse; assess timing and offer the most effective suitable option
1.5 mg
Oral
Once, as soon as possible
Single treatment, ideally ≤72 h; CDC allows emergency pills within 5 days, with reduced LNG effectiveness late in the window · One 1.5 mg tablet (or two 0.75 mg tablets together). If vomiting within 3 h, repeat the dose promptly (CDC)
  • Ulipristal or copper IUD may be more effective later in the 5-day window; do not apply ulipristal’s delayed hormonal-restart rule to LNG.
1.5 mg initial course; enzyme-inducing medicines need a separate EC plan, preferably copper IUD when suitable
Monitor
  • Pregnancy test if no withdrawal bleed/period within 3 weeks; assess pregnancy symptoms or abdominal pain
  • Can start/resume hormonal contraception immediately after LNG, using condoms/abstinence for 7 days
Contraindications / cautions
  • No benefit for an established pregnancy; does not protect against STIs or later unprotected intercourse
Pregnancy safety
No effect on established pregnancy
Lactation
Compatible
CDCcheckedIN REVIEW