Levonorgestrel IUS 52 mg

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

Levonorgestrel IUS 52 mgIntrauterine progestogen

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Levonorgestrel IUS 52 mg: indication-specific regimens
Indication	Dose	Route	Frequency	Duration / preparation	Maximum	Monitoring / cautions
Heavy menstrual bleeding after evaluating uterine/cervical/endometrial pathology Bayer / emcchecked	One 52 mg intrauterine system	Intrauterine	One insertion by a trained clinician	5 years for HMB, then reassess symptoms; replace/remove if bleeding returns · Sterile, single-use Mirena system and inserter; aseptic insertion after assessment of uterine position/cavity and infection/pregnancy exclusion. Record insertion date and indication-specific removal date 52 mg systems/indications are not interchangeable with lower-dose IUS products. HMB symptom recurrence requires reassessment before assuming device failure.	One device; contraception duration (8 years) must not be applied to HRT endometrial protection (4 years in the UK label)	Monitor Bleeding/pain, expulsion/perforation symptoms, thread/insertion follow-up and pregnancy symptoms; investigate persistent/new abnormal bleeding Contraindications / cautions Pregnancy, active pelvic/cervical infection, unexplained bleeding until assessed, uterine cavity distortion, current hormone-dependent tumour or acute severe liver disease
Contraception after pregnancy exclusion and eligibility assessment Bayer / emcchecked	One 52 mg intrauterine system	Intrauterine	One insertion by a trained clinician	Up to 8 years for contraception with this specific Mirena 52 mg product · Sterile, single-use Mirena system and inserter; aseptic insertion after assessment of uterine position/cavity and infection/pregnancy exclusion. Record insertion date and indication-specific removal date 52 mg systems/indications are not interchangeable with lower-dose IUS products. HMB symptom recurrence requires reassessment before assuming device failure.	One device; contraception duration (8 years) must not be applied to HRT endometrial protection (4 years in the UK label)	Monitor Bleeding/pain, expulsion/perforation symptoms, thread/insertion follow-up and pregnancy symptoms; investigate persistent/new abnormal bleeding Contraindications / cautions Pregnancy, active pelvic/cervical infection, unexplained bleeding until assessed, uterine cavity distortion, current hormone-dependent tumour or acute severe liver disease

Pregnancy safety

Exclude pregnancy before insertion; assess postpartum timing and perforation risk

Lactation

Assess insertion timing and product-specific postpartum precautions

Bayer / emccheckedIN REVIEW