Lorazepam — status epilepticus

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

Lorazepam — status epilepticusEMERGENCY KITEmergency Drugs

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Lorazepam — status epilepticus: indication-specific regimens
Indication	Dose	Route	Frequency	Duration / preparation	Maximum	Monitoring / cautions
Seizure lasting ≥5 min or recurrent seizures without recovery; also assess/treat eclampsia when possible NHS Greater Glasgow and Clydechecked	2 mg IV over 1 min; if not terminating, another 2 mg after 2–3 min (up to 4 mg); a repeat benzodiazepine dose at 10 min if still seizing under the GGC pathway	Slow IV	Initial staged dose; at most one repeat treatment before moving to second-line therapy	Time-critical rescue; prepare airway/ventilation and second-line therapy concurrently · Use the actual IV lorazepam product; dilute according to its label. Prescribe in mg and verify mg/mL, including any dilution	4 mg initial treatment; count any benzodiazepine already given. Persistent status needs second-line loading and ICU, not endless benzodiazepines	Monitor Airway, respiratory rate, SpO2, BP, ECG and glucose; assisted ventilation capability immediately available Contraindications / cautions Respiratory depression is a major risk, especially after prior sedatives; do not mix several benzodiazepine schedules

Pregnancy safety

Time-critical seizure treatment with airway support; distinguish eclampsia and its magnesium regimen.

Lactation

Acute maternal stabilisation takes priority; review ongoing treatment and infant exposure with the linked source and specialist team.