Norepinephrine (noradrenaline)

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

Norepinephrine (noradrenaline)EMERGENCY KITEmergency Drugs

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Norepinephrine (noradrenaline): indication-specific regimens
Indication	Dose	Route	Frequency	Duration / preparation	Maximum	Monitoring / cautions
Persistent shock while fluid responsiveness/source control are addressed; first-line vasopressor in maternal septic shock MSFchecked	Start 0.1 microgram/kg/min of NOREPINEPHRINE TARTRATE; increase by 0.05 microgram/kg/min as required	IV infusion pump through a suitable monitored large vein	Continuous infusion; MSF reassessment/titration every 10 min initially	Until perfusion and BP recover; taper gradually, do not stop abruptly · For the cited stock 8 mg TARTRATE/4 mL (=4 mg BASE/4 mL): 2 mL contains 4 mg tartrate. Add 38 mL compatible fluid for FINAL 40 mL =100 micrograms TARTRATE/mL. Rate = dose × kg ×60 ÷100 mL/h; at 70 kg and 0.1, rate=4.2 mL/h	MSF peripheral protocol ceiling 1 microgram/kg/min TARTRATE; persistent/escalating shock requires ICU and central/arterial access planning	Monitor Continuous ECG, frequent BP (arterial when possible), perfusion and urine output; inspect peripheral site frequently for extravasation Clearly label SALT versus BASE: this MSF tartrate dose is twice the numerical BASE dose; NEVER copy its pump rate into a base-labelled concentration Contraindications / cautions Correct hypovolaemia in parallel; vasopressors do not replace haemorrhage control/blood replacement Extravasation threatens tissue; use a dedicated monitored line, not an unobserved small distal cannula

Pregnancy safety

Life-saving vasopressor when indicated; specify TARTRATE versus BASE.

Lactation

Acute maternal stabilisation takes priority; review ongoing treatment and infant exposure with the linked source and specialist team.