Micronised progesterone for HRT

Pregnancy & gynaecology-specific. Every dose row is source-referenced; verify against institutional protocols.

Micronised progesterone for HRTProgestogen / endometrial protection

Regimens checked: 2026-10-17. Each indication has its own preparation, limits and safety checks.

Micronised progesterone for HRT: indication-specific regimens
Indication	Dose	Route	Frequency	Duration / preparation	Maximum	Monitoring / cautions
Endometrial protection with standard-dose systemic oestrogen in a patient with a uterus British Menopause Societychecked	200 mg at bedtime for 12–14 days in each 28-day/monthly cycle	Oral	Nightly on the prescribed 12–14 days each cycle	For as long as systemic oestrogen is used with an intact uterus; review bleeding and increase protection if oestrogen dose increases · Use oral micronised-progesterone capsules: 200 mg =two 100 mg capsules where that is the available strength. Do not substitute an unverified compounded or vaginal product Choose sequential or continuous treatment according to menopausal phase and clinical assessment; never omit protection because a patch is used.	This standard-dose-oestrogen schedule is 200 mg cyclic OR 100 mg daily, not both; high-dose oestrogen needs a revised progestogen prescription	Monitor Sedation, adherence to the full monthly course and new/persistent unscheduled bleeding Contraindications / cautions Unexplained bleeding, hormone-dependent malignancy or serious liver disease require assessment; check the actual capsule excipients/allergies
Endometrial protection with standard-dose systemic oestrogen in a patient with a uterus British Menopause Societychecked	100 mg at bedtime every day	Oral	Every night continuously	For as long as systemic oestrogen is used with an intact uterus; review bleeding and increase protection if oestrogen dose increases · Use oral micronised-progesterone capsules: 200 mg =two 100 mg capsules where that is the available strength. Do not substitute an unverified compounded or vaginal product Choose sequential or continuous treatment according to menopausal phase and clinical assessment; never omit protection because a patch is used.	This standard-dose-oestrogen schedule is 200 mg cyclic OR 100 mg daily, not both; high-dose oestrogen needs a revised progestogen prescription	Monitor Sedation, adherence to the full monthly course and new/persistent unscheduled bleeding Contraindications / cautions Unexplained bleeding, hormone-dependent malignancy or serious liver disease require assessment; check the actual capsule excipients/allergies

Pregnancy safety

These are menopause HRT regimens, not miscarriage/luteal-support doses

Lactation

HRT schedules are not indicated during breastfeeding

British Menopause SocietycheckedIN REVIEW