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Medical Disorders in Pregnancy

Chronic Medical Disorders Quick-Reference (asthma · epilepsy · cardiac · CKD · SLE/APS)

IN REVIEWv2🌍 International referencePENDING CLINICAL VERIFICATION
Continuity beats novelty: keep effective pre-pregnancy regimens (with teratogen switches), monitor organ function each trimester, plan birth in appropriately equipped units.

Admission & discharge ↓

Reviewer note: Condensed index module - each domain deserves full expansion in v1.1 content cycle. Admission/discharge guidance checked 18 October 2026. This adds a scoped clinical synthesis and does not certify every statement in the module.

Admission & discharge

Care setting: Stable disease: coordinated outpatient care; acute decompensation: hospital assessment

Admission/discharge guidance checked 2026-10-18 against the linked sources. This is a clinical checklist for an individual decision, not an automatic discharge order.

Triage and handover guidance for a multi-condition index. This is not a complete asthma, epilepsy, cardiac, renal or autoimmune discharge protocol; the relevant specialty plan must be attached.

When admission or continued hospital care is needed

  • Severe breathlessness/hypoxia, chest pain/syncope, prolonged/recurrent seizure, acute kidney injury/oliguria, severe hypertension or systemic autoimmune/obstetric deterioration requires urgent hospital assessment and appropriate admission.

When clinic, day care or home care may be suitable

  • A stable chronic diagnosis alone does not mandate admission. A named respiratory, neurological, cardiac, renal or rheumatology plan is required for the actual condition.

Before going home

  • The acute problem is resolved and the relevant specialty has agreed treatment, monitoring and the safe care setting.
  • Persistent organ dysfunction, oxygen/infusion requirements or an unexplained seizure must not be covered by a generic discharge checklist.

Discharge medicines and treatment changes

  • Reconcile each disease-specific medicine, pregnancy/postpartum changes, renal dosing and breastfeeding safety. Do not abruptly stop essential anti-seizure, cardiac or steroid treatment without a specialist plan.

Tests, pending results and their reviewer

  • Document the actual disease/organ results, pending investigations and named specialty reviewer; test schedules depend on that diagnosis.

Home care and counselling

  • Give an illness-specific action plan, medication access and clear emergency contacts.

Follow-up: when and what to review

WhenAction / responsible service
Before leaving
Book the actual specialty/maternity follow-up and tests for the diagnosed condition.
After birth or a major medicine change
Arrange early reassessment rather than assuming the prepregnancy regimen remains suitable.

Return urgently

  • Breathlessness, chest pain, collapse, seizure, severe headache, reduced urine or rapid deterioration needs urgent hospital care.

Open the complete discharge checklist →

Treatment

① Immediate stabilization — first minutes

Domain-specific emergencies follow their modules; this page is a continuity checklist.

③ First-line treatment & drug regimens
  • Booking: medication reconciliation against TERATOGEN list; specialist letters obtained
  • Trimester checkpoints: disease activity labs + organ function
  • Birth planning: unit capability matched to mWHO/CKD stage/SLE activity
  • Postpartum: flare windows (SLE), medication continuation, lactation compatibility table applied
Monitoring
  • Individualised per condition above
Escalation
  • Joint clinics (obstetric-medicine) strongly recommended
⑮ Complications & their management
Flare vs PE confusion

Complement levels, anti-dsDNA, proteinuria trend differentiate

Post-treatment care
  • 6-week specialist review each condition

Principles & follow-up

Special situations
ConditionPregnancy-critical points
Asthma
ICS safe & essential - undertreatment kills; LABA continue; montelukast OK; acute attack treated FULLY (O2+SABA+steroids); fetal hypoxia is the danger
Epilepsy
NEVER abrupt-stop ASM; lamotrigine/levetiracetam favoured (levels fall - increase doses!); valproate avoid where possible; folic acid 5 mg/day; single-drug lowest-effective principle
Cardiac disease
mWHO classification drives unit level; NYHA reviews each trimester; endocarditis prophylaxis per lesion policy; anticoagulation switches managed by cardiology; watch heart-failure window 28-34 wks + postpartum
CKD
Stage-linked risks; BP target <140/90 with labetalol/nifedipine; aspirin; nephrology co-care; ACEi/ARB stopped pre-conception (enalapril OK postpartum/lactation)
SLE
Plan conception in quiet disease (hydroxychloroquine CONTINUE - protective); azathioprine/calcineurin-inhibitors compatible; mycophenolate/cyclophosphamide STOP; neonatal lupus (anti-Ro) surveillance; flares vs PE differentiation
APS
Obstetric APS: aspirin + prophylactic LMWH from positive test; thrombotic APS: therapeutic LMWH; platelet watch

Sources (6)

WHO — WHO recommendations on antenatal care for a positive pregnancy experience (+ updates: MMN supplements, vitamin D, zinc, ultrasound before 24 weeks; WHO Maternal Health recommendations 2nd ed 2025)
2016; updates 2020–2025 (2nd ed maternal-health compendium 2025-03) · checked 2026-08-23 · verified-live
Open source ↗

WHO pages + NCBI compendium: daily IFA 30–60 mg elemental iron + 400 µg folic acid; intermittent IFA only where daily not acceptable & anaemia prevalence <20%; anaemia in ANC → 120 mg elemental iron daily until Hb normal; MMS recommended only within rigorous research contexts (supersedes 2016); ≥8 c…

NICE — Acutely ill adults in hospital — CG50
· checked 2026-10-18 · verified-live
Open source ↗

Full primary recommendations read, focusing on critical-care-to-ward transfer: structured written handover, shared plan, monitoring, rehabilitation and receiving-team capability. Step-down is distinct from home discharge; no universal organ-support discharge cutoff is asserted.

NICE — Postnatal care — NG194
· checked 2026-10-18 · verified-live
Open source ↗

Maternal/newborn transfer assessment, first void and effective feeding, handover, support/safeguarding, first midwife visit within 36 hours after transfer, postnatal danger symptoms. Full recommendations page read.

India MoHFW / NHM — District Hospital Standard Operating Procedures — LaQshya
· checked 2026-10-18 · verified-live
Open source ↗

Normal-delivery discharge not less than 48 hours: full primary SOP PDF normal-delivery/discharge passages read. Corroborated by NHM CEmONC 2024 Part 1, chapter 8. This does not define a universal post-caesarean or complicated-case stay.

WHO — WHO recommendations on quality postnatal care — official recommendation summary
· checked 2026-10-18 · verified-live
Open source ↗

Official WHO summary read: at least 24-hour facility care after birth; additional contacts at 48–72 hours, 7–14 days and week 6; individual assessment/support. Summary facts only, not a claim that the full 242-page PDF was reviewed.

RCOG — Laparoscopy — recovering well
· checked 2026-10-18 · verified-live
Open source ↗

Full primary patient recovery page read: pain control, wounds, activity/VTE, urinary/bowel and infection warning signs, adult support and no driving/important decisions during the first 24 hours after general anaesthesia. Used as general recovery/handover principles, not operation-specific discharge…