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Obstetrics

Fetal Growth Restriction / SGA

IN REVIEWv3🌍 International referencePENDING CLINICAL VERIFICATION
SGA = size <10th centile; FGR = failure to reach genetic potential (pathology). Doppler-driven management: UA/MCA/DV surveillance, steroids <34+6 at risk of birth, MgSO4 <32, deliver by severity trajectory - not by centile alone.

Admission & discharge ↓

Reviewer note: Medication regimens and dependent emergency instructions checked 17 October 2026. These targeted checks do not certify every statement in the module. Admission/discharge guidance checked 18 October 2026. This adds a scoped clinical synthesis and does not certify every statement in the module.

Clinical detail

Additional detail checked 2026-10-17 against the linked sources. This check covers the section below; the rest of the module retains its displayed verification status.

A small estimated fetal size can reflect constitutional smallness or growth restriction. The clinical task is to assess growth trajectory, placental function and the wider pregnancy picture.

Assessment & interpretation

  • Review dating, maternal risks, previous fetal-growth history and serial measurements.
  • Use appropriate ultrasound assessment of growth, amniotic fluid and umbilical-artery Doppler; additional investigations depend on how early and how severely growth is affected.

Decisions that change management

  • Arrange a surveillance plan with intervals and escalation criteria suited to the findings.
  • Timing and mode of birth depend on fetal wellbeing, gestation and the balance between remaining in utero and prematurity; a percentile alone is not the entire decision.
  • Maternal hypertension and other placental-disease features require concurrent assessment.

Follow-up & safety-netting

  • Explain how to seek help for reduced movements, including between scheduled scans.
  • Before planned preterm birth, discuss neonatal support and indicated antenatal treatment.
  • Review newborn growth and the pregnancy outcome, and record what surveillance may be needed next pregnancy.

Clinical pitfalls

  • Growth and Doppler results answer different questions. A single reassuring measurement should not erase a concerning trend or new maternal or fetal symptoms.
Sources for this detail:

Admission & discharge

Care setting: Specialist surveillance; admit if maternal/fetal findings require closer care or birth

Admission/discharge guidance checked 2026-10-18 against the linked sources. This is a clinical checklist for an individual decision, not an automatic discharge order.

When admission or continued hospital care is needed

  • Abnormal/worsening fetal assessment, concerning Doppler findings, reduced movements, maternal hypertension or another complication may require admission and delivery planning.

When clinic, day care or home care may be suitable

  • Selected stable FGR/SGA can be followed with a written schedule of growth, Doppler and other fetal surveillance and a planned birth date.

Before going home

  • The specialist team has reviewed current growth/Doppler/fetal wellbeing and documented why the surveillance interval and location are safe.
  • The patient has reliable access to the next test and urgent assessment; do not discharge with only a generic repeat scan in a few weeks.

Discharge medicines and treatment changes

  • Record any antenatal steroid/neuroprotection course and remaining appointments; no unproven home drug is prescribed merely to increase fetal growth.

Tests, pending results and their reviewer

  • Give exact scan/Doppler/CTG dates according to the diagnosed severity and gestation, plus the responsible reviewer.

Home care and counselling

  • Explain reduced-movement reporting and the circumstances that would bring birth forward.

Follow-up: when and what to review

WhenAction / responsible service
At the booked specialist surveillance contacts
Review fetal and maternal findings and update timing/place of birth.
Immediately for reduced movements/new symptoms
Reassess rather than waiting for the next scan.

Return urgently

  • Reduced/absent movements, bleeding, fluid loss, severe headache/visual symptoms or abdominal pain requires prompt maternity assessment.

Open the complete discharge checklist →

Treatment

① Immediate stabilization — first minutes

Not acute unless CTG pathological -> birth pathway.

③ First-line treatment & drug regimens
  • LATE-ONSET FGR (>=32 wks): surveillance 2x weekly (CTG+UA); DELIVER ~37 wks when SGA with risk factors (NICE-style), earlier on deterioration
  • EARLY-ONSET (<32 wks): intensive pathway - steroids complete if birth likely, MgSO4 <30-32, deliver on DV abnormality/reversed AEDF/CTG loss; expectancy only in tertiary centres with daily review
  • Aspirin next-pregnancy prevention discussion; treat maternal disease aggressively
Betamethasone — antenatal courseWHOsummary checked
Dose12 mg IM, then 12 mg IM 24 hours later
RouteIM
FrequencyTwo doses, 24 h apart
DurationOne 24 mg course. Consider only ONE repeat course under NICE criteria; not routine weekly courses
PreparationConfirm product strength: for 6 mg/mL, 12 mg = 2 mL; volumes differ by formulation. Use the obstetric IM preparation
Max dose24 mg/course; NICE permits no more than 2 courses in total under its repeat-course criteria
  • Imminent preterm birth within the guideline gestational window; do not delay urgent maternal/fetal delivery
  • NICE offers at 24+0–33+6 weeks, considers 34+0–35+6; individual discussion at 22+0–23+6. Repeat: <34 weeks, prior course >7 days ago and very high risk of birth in 48 h.
Monitoring
  • Glucose monitoring and an insulin-adjustment plan in diabetes; assess infection and timing of birth
Contraindications: Do not delay lifesaving delivery to complete steroids; do not use a blanket “infection contraindication” without senior assessment
④ Drug treatment detail (2 agents)
Dexamethasone — antenatal alternativeWHOsummary checked
Dose6 mg IM every 12 h for four doses
RouteIM
FrequencyEvery 12 hours, four doses
Duration24 mg total over 36 h; ONE course, subject to the same repeat-course restrictions
PreparationCheck the injectable product: if 4 mg/mL, 6 mg = 1.5 mL; other strengths require recalculation. Give IM for this antenatal regimen
Max doseFour 6 mg doses = 24 mg/course; do not combine with a full betamethasone course
  • Indication: Alternative fetal-lung-maturation course when appropriate
Monitoring
  • Maternal glucose, infection assessment and birth timing; diabetes team plan
Contraindications: Do not prolong an unsafe pregnancy to finish the course
Magnesium sulfate — fetal neuroprotectionNICE · NG25checked
Dose4 g over 15 min, then 1 g/hour
RouteIV infusion
FrequencyLoading once, then continuous infusion
DurationStop at birth or 24 hours, whichever occurs first
Preparation50%: 4 g = 8 mL diluted in compatible sodium chloride 0.9%; maintenance example 20 g made up to FINAL 100 mL, 5 mL/hour via pump
Max dose24 hours for neuroprotection; do not add to an eclampsia regimen already running
  • Indication: Imminent preterm birth: NICE offers at 24+0–29+6 weeks and considers at 30+0–33+6 weeks; discuss 23+0–23+6 individually
Monitoring
  • Record pulse, BP, respiratory rate and tendon reflexes at least every 4 h; more often if oliguria or renal impairment
Contraindications: Myasthenia gravis, heart block or magnesium toxicity · Renal impairment or oliguria requires reduced/withheld maintenance and more frequent assessment
Definitive treatment

BIRTH remains the only definitive therapy once fetus outgrows placental support.

Monitoring
Severity bandSurveillance
SGA, normal Dopplers
Growth q2-3 wks + UA q1-2 wks + CTG weekly-ish per unit
AEDF present
Hospital-based: UA/MCA/DV 2-3x weekly + daily CTG
REDF/DV absent-flow
Daily assessment; delivery decision imminent
Response assessment
  • Stable Doppler trends; growth continuing along its curve
Treatment failure
  • Deterioration cascade -> escalate frequency then deliver
Escalation
  • Early-onset severe FGR belongs in units with NICU + fetal-medicine expertise - transfer BEFORE crisis
⑮ Complications & their management
Stillbirth

Timely delivery is the preventable lever; document surveillance compliance

Neonatal hypoglycaemia/polycythaemia

Paediatric anticipation at birth

Post-treatment care
  • Placental histology request
  • Next-pregnancy aspirin ± LMWH (APS cases) planning

Diagnosis & assessment

Red flags:
  • Absent/reversed end-diastolic flow in umbilical artery (EARLY-onset marker)
  • Reduced variability/abnormal CTG
  • MCA PI fall + DV abnormality (late decompensation)
  • Maternal hypertension/proteinuria emerging alongside

Definition: SGA: EFW/AC below 10th customised centile. FGR: placenta-mediated failure to achieve growth potential (may be normal-size!). Early-onset (<32 wks) vs late-onset (>=32 wks) differ in surveillance/delivery logic.

Risk factors

Severe pre-eclampsia/hypertensionPrevious FGR/stillbirthSmokingLow PAPP-aAntiphospholipid syndromeMaternal disease (CKD/anaemia/thalassaemia)Multiple pregnancy discordanceTeratogens/malaria/TORCH where relevant

Initial assessment

  1. Confirm dating accuracy first!
  2. Customised growth charting (inter-growth/WHO standards where applicable)
  3. UA Doppler + amniotic fluid; MCA PI from 26-28 wks context
  4. Screen maternal causes: BP panel, anaemia, infection history, substance use
  5. Classify: early vs late onset; SGA-with-normal-Doppler vs true FGR

Investigations

TestLooking for
Umbilical artery PI trend
Core surveillance axis (q1-3 wks by severity)
MCA PI
Brain-sparing sign in late-onset deterioration
Ductus venosus + CTG (early-onset severe)
Timing decisions <32 wks
Maternal panel + TORCH where indicated
Reversible/non-placental causes

Principles & follow-up

Management principles

Sources (10)

RCOG — Antenatal Corticosteroids to Reduce Neonatal Morbidity and Mortality (Green-top Guideline No. 74)
2022-02 · checked 2026-08-23 · pending-verification
Open source ↗

Cited via RCOG GTG73 update note; direct PDF audit pending — flag

RCOG — Having a small baby — patient information
· checked 2026-10-18 · verified-live
Open source ↗

Scope: additional clinical-detail explanation for fgr. Checked the assessment, management-decision and follow-up statements in that section against this source. This does not certify all pre-existing regimens, calculations or recommendations in the module. Additional admission/discharge check 18 Oct…

WHO — Antenatal corticosteroids for improving preterm birth outcomes — 2022
· checked 2026-10-17 · verified-summary
Open source ↗

Recommendation 1.9/type-and-regimen evidence: IM dexamethasone or betamethasone total 24 mg; four 6 mg dexamethasone doses 12 hours apart or two 12 mg betamethasone doses 24 hours apart. NICE NG25 supplies gestational and repeat-course criteria.

NICE — NG25 — preterm labour and birth
20 November 2015 · updated 10 June 2022 · checked 2026-10-18 · verified-live
Open source ↗

Scope: additional clinical-detail explanation for ptl-threatened, ptl-established. Checked the assessment, management-decision and follow-up statements in that section against this source. This does not certify all pre-existing regimens, calculations or recommendations in the module. Additional admi…

NICE — NG133 — hypertension in pregnancy
25 June 2019 · updated 17 April 2023 · checked 2026-10-18 · verified-live
Open source ↗

Scope: additional clinical-detail explanation for hdp-postpartum. Checked the assessment, management-decision and follow-up statements in that section against this source. This does not certify all pre-existing regimens, calculations or recommendations in the module. Targeted medication audit: Table…

NICE — Postnatal care — NG194
· checked 2026-10-18 · verified-live
Open source ↗

Maternal/newborn transfer assessment, first void and effective feeding, handover, support/safeguarding, first midwife visit within 36 hours after transfer, postnatal danger symptoms. Full recommendations page read.

India MoHFW / NHM — District Hospital Standard Operating Procedures — LaQshya
· checked 2026-10-18 · verified-live
Open source ↗

Normal-delivery discharge not less than 48 hours: full primary SOP PDF normal-delivery/discharge passages read. Corroborated by NHM CEmONC 2024 Part 1, chapter 8. This does not define a universal post-caesarean or complicated-case stay.

WHO — WHO recommendations on quality postnatal care — official recommendation summary
· checked 2026-10-18 · verified-live
Open source ↗

Official WHO summary read: at least 24-hour facility care after birth; additional contacts at 48–72 hours, 7–14 days and week 6; individual assessment/support. Summary facts only, not a claim that the full 242-page PDF was reviewed.

RCOG — Laparoscopy — recovering well
· checked 2026-10-18 · verified-live
Open source ↗

Full primary patient recovery page read: pain control, wounds, activity/VTE, urinary/bowel and infection warning signs, adult support and no driving/important decisions during the first 24 hours after general anaesthesia. Used as general recovery/handover principles, not operation-specific discharge…

NICE — Acutely ill adults in hospital — CG50
· checked 2026-10-18 · verified-live
Open source ↗

Full primary recommendations read, focusing on critical-care-to-ward transfer: structured written handover, shared plan, monitoring, rehabilitation and receiving-team capability. Step-down is distinct from home discharge; no universal organ-support discharge cutoff is asserted.