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Obstetrics

Placenta Accreta Spectrum (acreta/increta/percreta)

IN REVIEWv2🌍 International referencePENDING CLINICAL VERIFICATION
Abnormal placental invasion through the decidua — the modern maternal-surgery killer (praevia + previous caesarean is the classic setup). OUTCOME IS PLANNED: detect on imaging, refer to a centre with blood bank + IR + urology, deliver electively 35–37 wks with multidisciplinary team.

Admission & discharge ↓

Reviewer note: Admission/discharge guidance checked 18 October 2026. This adds a scoped clinical synthesis and does not certify every statement in the module.

Admission & discharge

Care setting: Planned specialist-centre admission; urgent admission for bleeding/labour

Admission/discharge guidance checked 2026-10-18 against the linked sources. This is a clinical checklist for an individual decision, not an automatic discharge order.

When admission or continued hospital care is needed

  • Bleeding, labour, membrane rupture, maternal deterioration or fetal concern requires hospital assessment. Planned birth should be in an appropriately resourced multidisciplinary centre.

When clinic, day care or home care may be suitable

  • Stable antenatal PAS may be followed by a specialist team until the planned admission; outpatient care needs a documented emergency-access plan.

Before going home

  • After surgery, no recurrent bleeding, sepsis or unresolved organ-support need; bowel, bladder, pain, mobility and nutrition are satisfactory.
  • Document any urinary tract injury, hysterectomy, retained placenta/conservative management, drains or planned further procedures. Conservative PAS management needs an explicit prolonged follow-up pathway.

Discharge medicines and treatment changes

  • Provide the actual anaemia, analgesia and VTE-prevention prescription with stop/review dates; antimicrobial treatment is indication-specific.

Tests, pending results and their reviewer

  • Assign review of pathology, Hb/renal findings and outstanding imaging or specialist results.

Home care and counselling

  • Teach wound/drain/catheter care when applicable; discuss fertility consequences, future-pregnancy planning and emotional recovery.

Follow-up: when and what to review

WhenAction / responsible service
Before discharge
Name the lead obstetric/surgical team and dates for wound, blood, urinary and pathology reviews.
If placenta retained/conservative treatment
Provide a specialist monitoring schedule and rapid-return access; ordinary post-caesarean discharge advice alone is insufficient.

Return urgently

  • Heavy bleeding, fever, worsening pain, urinary problems, breathlessness or collapse require immediate assessment.

Open the complete discharge checklist →

Treatment

① Immediate stabilization — first minutes
  • Unsuspected finding at caesarean: DO NOT pull the placenta — call senior help, close over placenta in situ (conservative bridge) and transfer to capable centre OR convert to caesarean hysterectomy if team assembled
  • Never piecemeal-remove an accreta
③ First-line treatment & drug regimens
  • PLANNED MULTIDISCIPLINARY CAESAREAN HYSTERECTOMY (standard recommended management) at 35+0–36+6 weeks (earlier 34+0–35+0 for bleeding episodes/extreme invasion)
  • Conservative management (leaving placenta in situ/methotrexate-assisted resorption) = SELECTED EXPERT-CENTRE ALTERNATIVE only — high risks: infection, haemorrhage, late hysterectomy, GTN-confounding follow-up
  • Cell salvage + rapid infuser prepared; 4–6 units crossmatched minimum (complex: 10+)
  • Prophylactic internal iliac balloon occlusion/pre-operative embolisation: institution-dependent evidence — use per local protocol
Definitive treatment
  1. THEATRE SEQUENCE (planned case):
  2. 1. Regional±GA strategy per anaesthetics (long case; GA conversion readiness)
  3. 2. Midline/transverse access chosen for exposure; bladder flap HIGH
  4. 3. Fetus delivered via incision AVOIDING placenta (transverse fundal where anterior percreta)
  5. 4. Cord clamped; NO placental traction
  6. 5. Hysterectomy performed WITH placenta in situ (total hysterectomy ± parametrial dissection per grade)
  7. 6. Bladder cystotomy repair/ureteric stenting as mapped pre-op by urology
  8. 7. Haemostasis layer-wise; packing option; IR embolisation on standby
Monitoring
PhaseWatch
Intra-op
Cumulative blood loss >2 L → activate MTP formally
HDU/ICU 24–48 h
Ongoing ooze, urine output, coags, bladder drain contents (haematuria)
Day 2–5
Ileus, infection, VTE prophylaxis timing, wound
Response assessment
  • Stable counts/coags
  • Drains dry/declining
  • Ambulating; bowel function returning
Treatment failure
  • Re-look laparotomy for bleeding → IR embolisation → packing + damage-control closure
  • Urine leak → urology re-imaging (CT urogram) + stent revision
Second-line treatment
  • Delayed-interval approach complications managed jointly (sepsis → antibiotics ± completion hysterectomy; secondary haemorrhage → embolisation)
Rescue treatment

Catastrophic haemorrhage: aortic compression/clamp, massive transfusion ratios, damage-control surgery with packing + transfer to ICU, re-look in 24–48 h.

Procedure / surgery

Detailed operative pages: see procedures-caesarean-hysterectomy (linked).

Escalation
  • ALL suspected/confirmed PAS births belong in centres with: 24/7 blood bank incl. massive supply, interventional radiology, urology, experienced obstetric surgeon, ICU, neonatal unit
  • In-utero transfer BEFORE labour beats emergency retrieval
⑮ Complications & their management
Massive haemorrhage

MTP activation; ratio components; cell salvage; consider rFVIIa adjunct only after physiology corrected

Bladder/ureteric injury

Intra-op urology repair; stents 6 weeks; post-op cystogram/urogram

VTE

Extended prophylaxis post-discharge (28 days) balancing bleeding risk

Psychological trauma/fertility loss

Debrief; counselling referral; documented fertility discussion pre-operatively

Post-treatment care
  • Histopathology confirmation
  • 6-week pelvic review; urinary function check
  • Contraception: permanent methods discussion appropriate
  • Next pregnancy impossible without uterus — document counselling

Diagnosis & assessment

Red flags:
  • Praevia + ≥1 prior caesarean → SCREEN EVERY CASE
  • Loss of retroplacental clear zone
  • Numerous placental lacunae (grade 2–3)
  • Bladder wall interruption + subplacental hypervascularity
  • Abnormal fetal-MRI findings where used

Definition: Accreta (attached to myometrium), increta (into myometrium), percreta (through serosa ± adjacent organs). FIGO/AIP classification grades 1–3 based on topography.

Risk factors

PLACENTA PRAEVIA + PRIOR CAESAREAN (synergistic — risk rises steeply with number of scars)Any uterine scar (myomectomy)GrandmultiparityAsherman/previous curettageSubmucous fibroidsMaternal age

Presentation

  • Usually ANTENATAL IMAGE DETECTION
  • May present as APH/PFH at caesarean with placenta that will not separate
  • Percreta: haematuria, bladder symptoms, rectal bleeding rarely

Initial assessment

  1. Screening ultrasound (greyscale + colour Doppler) for ALL praevia-with-scar cases at anomaly scan (~18–22 wks) AND again ~28 wks
  2. Suspicion → REFER to accredited centre (FIGO-endorsed multidisciplinary model) — do not manage operatively in unequipped facilities
  3. MRI adjunct where topographic mapping needed (posterior/parametrial invasion, ureteric involvement)
  4. Multidisciplinary board: obstetrics, anaesthesia, interventional radiology, urology, neonatology, haematology, intensive care

Investigations

TestLooking for
TVS/TAS Doppler
Lacunae, clear-zone loss, bladder-line interruption, bridging vessels, subplacental vascularity
MRI pelvis (selected)
Depth/topography; parametrial/posterior extension; ureteric proximity
CBC, group&save, antibody screen
Transfusion planning; anaemia optimisation
Renal function ± CT urogram (percreta with urinary symptoms)
Ureteric involvement mapping

Algorithm

Entry pointPraevia + previous caesarean identified
ActionTargeted US Doppler screening (18–22 & 28 wks)
DecisionSigns of invasion?
ActionREFERRAL CENTRE: MDT board ± MRI · blood/IR/urology logistics
OutcomePlanned caesarean hysterectomy 35–37 wks (earlier if bleeding)

Sources (8)

WHO / FIGO / ICM — Consolidated guidelines for the prevention, diagnosis and treatment of postpartum haemorrhage
2025-10 · checked 2026-10-17 · verified-summary
Open source ↗

Targeted recheck: WHO 2025 recognition/treatment trigger (≥500 mL or ≥300 mL with abnormal haemodynamics), concurrent first-response bundle and refractory-haemorrhage fibrinogen target ≥2 g/L if replacing a level <2 g/L. Primary recommendation chapter/table indexed at https://www.ncbi.nlm.nih.gov/bo…

RCOG — Placenta praevia, placenta accreta and vasa praevia
· checked 2026-10-18 · verified-live
Open source ↗

Primary information read: individualised admission by bleeding/history/access, urgent attendance for bleeding/pain/contractions, specialist PAS/vasa praevia birth planning and postoperative/fertility counselling. No universal asymptomatic admission week is inferred.

NICE — NG192 — caesarean birth
31 March 2021 · updated 10 June 2025 · checked 2026-10-18 · verified-live
Open source ↗

Scope: additional clinical-detail explanation for lscs, vbac-tolac. Checked the assessment, management-decision and follow-up statements in that section against this source. This does not certify all pre-existing regimens, calculations or recommendations in the module. Additional admission/discharge…

RCOG — Laparoscopy — recovering well
· checked 2026-10-18 · verified-live
Open source ↗

Full primary patient recovery page read: pain control, wounds, activity/VTE, urinary/bowel and infection warning signs, adult support and no driving/important decisions during the first 24 hours after general anaesthesia. Used as general recovery/handover principles, not operation-specific discharge…

NICE — Postnatal care — NG194
· checked 2026-10-18 · verified-live
Open source ↗

Maternal/newborn transfer assessment, first void and effective feeding, handover, support/safeguarding, first midwife visit within 36 hours after transfer, postnatal danger symptoms. Full recommendations page read.

India MoHFW / NHM — District Hospital Standard Operating Procedures — LaQshya
· checked 2026-10-18 · verified-live
Open source ↗

Normal-delivery discharge not less than 48 hours: full primary SOP PDF normal-delivery/discharge passages read. Corroborated by NHM CEmONC 2024 Part 1, chapter 8. This does not define a universal post-caesarean or complicated-case stay.

WHO — WHO recommendations on quality postnatal care — official recommendation summary
· checked 2026-10-18 · verified-live
Open source ↗

Official WHO summary read: at least 24-hour facility care after birth; additional contacts at 48–72 hours, 7–14 days and week 6; individual assessment/support. Summary facts only, not a claim that the full 242-page PDF was reviewed.

NICE — Acutely ill adults in hospital — CG50
· checked 2026-10-18 · verified-live
Open source ↗

Full primary recommendations read, focusing on critical-care-to-ward transfer: structured written handover, shared plan, monitoring, rehabilitation and receiving-team capability. Step-down is distinct from home discharge; no universal organ-support discharge cutoff is asserted.