Postpartum Haemorrhage (PPH)
Admission & discharge
Admission/discharge guidance checked 2026-10-18 against the linked sources. This is a clinical checklist for an individual decision, not an automatic discharge order.
When admission or continued hospital care is needed
- Admit and treat ongoing heavy bleeding, abnormal haemodynamics, suspected retained tissue/infection or coagulopathy. Transfer to theatre/critical care according to bleeding and organ-support requirements.
When clinic, day care or home care may be suitable
- Active PPH, shock or suspected secondary PPH with systemic illness is not suitable for routine outpatient management.
Before going home
- The bleeding source is controlled; uterine/perineal/wound assessment is satisfactory and there is no recurrent concerning loss.
- Haemodynamics, consciousness, urine output, oral intake, mobility and pain control support home care. Review anaemia symptoms, Hb trend and any coagulopathy/organ injury; there is no single Hb value that alone certifies safe discharge.
Discharge medicines and treatment changes
- Prescribe iron replacement when iron deficiency/anaemia is present, using a documented formulation, dose and response plan; assess whether IV treatment or transfusion is needed before discharge.
- Uterotonics and TXA used for the acute event are not automatically continued at home. Reassess VTE prophylaxis after bleeding risk has fallen.
Medicine doses — use only when indicated
Use the medicines selected for this patient. Listed alternatives are not instructions to prescribe all of them together. Confirm the actual remaining course, pregnancy/postnatal context and monitoring plan.
Only for diagnosed postpartum iron-deficiency anaemia after bleeding is controlled.
- Indication: Diagnosed postpartum iron-deficiency anaemia after haemorrhage is controlled and outpatient oral treatment is suitable
- The WHO 2025 supportive-care recommendation supplies the postpartum dose/endpoint. Preparation and response monitoring reuse the checked oral-iron reference; breastfeeding is compatible with indicated maternal supplementation.
- Arrange Hb response review after 2–4 weeks, tolerance and adherence; investigate non-response or ongoing bleeding and reassess the replacement route.
- Review the cause of anaemia and any coexisting B12/folate deficiency or haemoglobinopathy.
Tests, pending results and their reviewer
- Record quantified loss, procedures, transfusion and latest relevant CBC/coagulation/renal results; assign a reviewer/date for outstanding investigations.
Home care and counselling
- Explain the cause and treatment, expected lochia, worsening-bleeding warnings, fatigue/feeding support and the future-birth haemorrhage plan. Offer a debrief and emotional support.
Follow-up: when and what to review
| When | Action / responsible service |
|---|---|
Before leaving | Book anaemia/Hb response review and communicate any organ-injury or transfusion follow-up to the responsible team. |
Early postnatal contacts and 6-week review | Review bleeding, recovery, mental health and the future-pregnancy plan; review sooner for symptoms or major anaemia. |
Return urgently
- Sudden/heavy or increasing bleeding, fainting, breathlessness, fever, offensive discharge or worsening abdominal pain require immediate assessment.
Treatment
① Immediate stabilization — first minutes
- Resuscitate and identify the cause IN PARALLEL: two large-bore IV cannulae, bloods/crossmatch and quantified cumulative loss; oxygen for hypoxia/shock, active warming and monitored fluid/blood replacement.
- Massage the uterus and use bimanual compression for atony; empty the bladder with a Foley catheter and measure urine output.
- Give oxytocin loading plus infusion and TXA using the complete cards below. Record previous prophylactic uterotonics: their identity changes the next uterotonic choice.
- For ongoing ATONIC bleeding, choose an appropriate additional uterotonic now: avoid ergometrine/methylergometrine with hypertension or pre-eclampsia, and avoid carboprost with asthma/significant pulmonary disease. Do not give both ergot preparations as though they are interchangeable.
- Keep examining the 4Ts while drugs are administered. Do not wait to finish eight carboprost doses before preparing tamponade or surgery in ongoing haemorrhage.
③ First-line treatment & drug regimens
- Atonic bleeding after delivery; treatment continues alongside the PPH bundle
- Quantified blood loss, uterine tone, BP/pulse, perfusion and urine output; record every dose and time
- Persistent shock or bleeding needs source control and blood products in parallel; do not wait for all drug doses
- Fluid balance, sodium if prolonged/high-volume treatment; cardiac disease needs a separately prescribed concentrated infusion
- PPH of any cause; first dose as soon as possible and WITHIN 3 h of birth
- Renal / hepatic: Renal clearance: assess renal function and seek dose advice with impairment; do not repeatedly dose without review
- Quantified blood loss, uterine tone, BP/pulse, perfusion and urine output; record every dose and time
- Persistent shock or bleeding needs source control and blood products in parallel; do not wait for all drug doses
- Atonic PPH after delivery; this is NOT the same formulation/dose as ergometrine
- The product label advises no breastfeeding during treatment and for at least 12 h after the last dose; express/discard milk during that interval.
- Quantified blood loss, uterine tone, BP/pulse, perfusion and urine output; record every dose and time
- Persistent shock or bleeding needs source control and blood products in parallel; do not wait for all drug doses
- BP before each dose; chest pain, vasospasm, headache and neurological symptoms
- Alternative uterotonic for atonic PPH; use this row only when the ampoule is ERGOMETRINE
- Quantified blood loss, uterine tone, BP/pulse, perfusion and urine output; record every dose and time
- Persistent shock or bleeding needs source control and blood products in parallel; do not wait for all drug doses
- BP before and after injection; chest pain, severe headache, peripheral ischaemia
- Refractory atonic PPH after first-line uterotonic; do not use for trauma or retained tissue alone
- Quantified blood loss, uterine tone, BP/pulse, perfusion and urine output; record every dose and time
- Persistent shock or bleeding needs source control and blood products in parallel; do not wait for all drug doses
- Respiratory status/bronchospasm, BP, vomiting/diarrhoea
- Atonic PPH when IV oxytocin is unavailable or bleeding does not respond; additional uterotonic selection depends on drugs already given
- Quantified blood loss, uterine tone, BP/pulse, perfusion and urine output; record every dose and time
- Persistent shock or bleeding needs source control and blood products in parallel; do not wait for all drug doses
- Temperature, shivering, gastrointestinal effects; distinguish drug fever from ongoing sepsis
Non-drug treatment
- Bimanual compression while preparing next step
- Non-pneumatic anti-shock garment (NASG) where available for transfer/stabilisation
- Warming (blankets/fluids) — hypothermia worsens coagulopathy
- Keep cumulative tally on whiteboard: EBL, products given, vitals timeline
Definitive treatment
- TONE: continue bimanual compression and the selected uterotonics. TRAUMA: inspect and repair tears/haematoma; assess rupture/inversion. TISSUE: arrange skilled manual removal/evacuation when indicated; do not forcibly detach a suspected accreta placenta. THROMBIN: correct coagulopathy with the blood bank while obtaining source control.
- If atony continues despite initial treatment, consider intrauterine balloon tamponade only after assessing trauma/retained tissue and where monitoring, blood and immediate surgical rescue are available. Use sterile technique, the specific balloon’s recommended filling fluid/volume and a drainage channel; record fill volume and continuing blood loss.
- Bakri-type devices have a manufacturer-specific maximum volume (commonly 500 mL); do not inflate repeatedly beyond the device limit to compensate for persistent bleeding. Continue observations, uterotonic support and an explicitly prescribed antibiotic/removal plan.
- Persistent bleeding, deteriorating physiology or a failed tamponade test means immediate senior operative control. Compression sutures/devascularisation, embolisation in a stable suitable patient, or hysterectomy are selected by cause and expertise; this is not a mandatory ladder requiring every step before hysterectomy.
Monitoring
| Parameter | During active major bleeding | Action / goal |
|---|---|---|
Blood loss, uterine tone, BP/pulse, perfusion, consciousness | Continuous/frequent reassessment with recorded trend | Continuing loss or shock → escalate source control immediately |
Urine output | Hourly via catheter | Target ≥0.5 mL/kg/h; interpret with overall perfusion |
CBC/platelets, PT/APTT, fibrinogen | Repeat during ongoing loss and after component replacement | Fibrinogen ≥2 g/L; platelets generally >50×10⁹/L during major bleeding |
Blood gas/lactate, ionised calcium, potassium, temperature | Serially during rapid transfusion | Correct abnormalities and maintain normothermia; no undefined calcium prescription |
Response assessment
- Bleeding slowing; firm uterus; balloon holding without refill
- Vitals normalising; urine output recovering
- Coags correcting; no progressive oozing
Treatment failure
Continuing loss or shock despite initial treatment: theatre and major-haemorrhage support immediately, without an arbitrary waiting period.
HDU/ICU for ongoing shock, vasopressor/ventilation need, coagulopathy, organ dysfunction or large transfusion; a unit count is not the sole admission criterion.
During transfer, continue uterine/aortic compression as appropriate, warming and blood/fluid support with skilled escort; contact the receiving team first. Compression/tamponade must not delay transfer or definitive rescue.
Second-line treatment
Refractory coagulopathy needs senior haemostatic assessment, appropriate fibrinogen/platelet/plasma replacement and source control; haemostatic rescue agents are not substitutes for these measures.
Rescue treatment
Activate major-haemorrhage support and definitive operative control early. If arrest occurs, follow maternal ALS with manual uterine displacement and immediate preparation for resuscitative birth at the arrest location.
Procedure / surgery
See procedures-mva (retained tissue), procedures-balloon-tamponade, procedures-blynch, procedures-peripartum-hysterectomy pages.
Escalation
Continuing loss or shock despite initial treatment: theatre and major-haemorrhage support immediately, without an arbitrary waiting period.
HDU/ICU for ongoing shock, vasopressor/ventilation need, coagulopathy, organ dysfunction or large transfusion; a unit count is not the sole admission criterion.
During transfer, continue uterine/aortic compression as appropriate, warming and blood/fluid support with skilled escort; contact the receiving team first. Compression/tamponade must not delay transfer or definitive rescue.
⑮ Complications & their management
DIC / dilutional coagulopathy
Ratio-based component therapy; fibrinogen replacement target ≥2 g/L; avoid FFP-only loops; recheck q1h
Dilutional thrombocytopenia
Platelets 1 pool per 6–8 units RBC or when <50×10⁹/L bleeding
Hypocalcaemia/hypothermia/acidosis (lethal triad partners)
Ionised Ca correction; active warming; ventilatory support for acidosis
Acute kidney injury
Volume restoration priority; avoid nephrotoxins; dialysis if AEIOU
Sheehan syndrome (late)
Post-event pituitary screen: prolactin/FT4/cortisol if lactation failure/fatigue; endocrinology referral
Secondary PPH
US for RPOC ± sepsis screen; antibiotics if infected; evacuation (MVA) with sepsis precautions; rare: GTN — send βhCG if persistent
Post-treatment care
- Anaemia correction: oral/IV iron per anaemia module; transfuse if symptomatic/Hb<70
- Thromboprophylaxis reassessed AFTER haemostasis (high VTE risk category)
- Lactation support; psychological debrief (PPH is traumatic)
- Document timeline + products + decisions; incident reporting/MTP audit
- Follow-up Hb check 2 weeks; contraception discussion delayed until stable
Diagnosis & assessment
- SHOCK INDEX (HR÷SBP) ≥0.9 — early hypovolaemia marker
- BP falling / HR rising / pallor-sweating
- Continued ooze with "normal" vitals in anaemic women (Hb<8 masks collapse)
- Boggy uterus despite massage
- Bleeding continuing after uterine contraction achieved → trauma/tissue/coagulopathy
- Oliguria <0.5 mL/kg/h
Definition: WHO 2025 adds the treatment trigger of ≥300 mL blood loss with abnormal vital signs to the traditional ≥500 mL threshold. Do not wait for 1000 mL after caesarean, a low Hb, or every classic shock sign before treating a deteriorating patient.
Risk factors
Initial assessment
- CALL FOR HELP — declare "PPH"; activate unit protocol; note time zero
- ABC: high-flow O₂ if shocked; position flat/left-lateral
- Two large-bore (14–16G) IV cannulae; send: CBC, crossmatch, coagulation (+fibrinogen), renal/liver, lactate where available
- Quantify blood loss (calibrated drape/weigh swabs) — visual estimation underestimates by 30–50%
- Palpate uterus → ATONIC? start massage immediately
- Empty bladder (catheter)
- Start crystalloid + oxytocin infusion while assessing cause (4Ts: Tone/Trauma/Tissue/Thrombin)
| Investigation | Purpose |
|---|---|
CBC + platelets (repeat q1–2h if major) | Baseline + trend; transfuse thresholds |
Group & save/CROSSMATCH | Component availability; MTP if ongoing |
PT/APTT/Fibrinogen (fibrinogen FIRST to fall in OB DIC) | Coagulopathy detection before overt oozing |
Lactate/ABG/ionised calcium | Shock depth; transfusion-related hypocalcaemia |
Bedside US | Retained tissue/free fluid; NOT a delay to treatment |
Differential diagnosis
| Condition | Clue |
|---|---|
Uterine atony (70–80%) | Soft boggy uterus; contracts with massage |
Genital tract trauma | Firm uterus + bright continuous bleeding — inspect cervix/vagina/perineum |
Retained tissue/placenta | Incomplete placenta/membranes; US shows retained products |
Coagulopathy/DIC | Oozing from IV sites, no formed clot; low fibrinogen first to fall |
Uterine inversion | Fundus not palpable/dimpled; mass at introitus (see emergency) |
Uterine rupture | Prior scar + fetal parts superficial + shock + CTG catastrophe |
Algorithm
Principles & follow-up
Management principles
Follow-up
- Hb recheck day 3 & 2 weeks
- Lactation/psychological support
- Future-pregnancy risk counselling + birth plan in equipped unit
Patient education
- Danger signs at home: heavy clots/soaking pad hourly, dizziness, fainting → return immediately
Sources (19)
2025-10 · checked 2026-10-17 · verified-summary
Open source ↗
Targeted recheck: WHO 2025 recognition/treatment trigger (≥500 mL or ≥300 mL with abnormal haemodynamics), concurrent first-response bundle and refractory-haemorrhage fibrinogen target ≥2 g/L if replacing a level <2 g/L. Primary recommendation chapter/table indexed at https://www.ncbi.nlm.nih.gov/bo…
2017 · checked 2026-10-17 · verified-live
Open source ↗
TXA 1 g IV over 10 minutes within three hours of birth; repeat 1 g for bleeding continuing at 30 minutes or recurring within 24 hours. The recurrence rule is for a second dose and does not permit a first dose beyond three hours. WHO 2025 recommendation text and original WHO dosing reviewed.
2023 · checked 2026-08-23 · verified-summary
Open source ↗
WHO landing page; detailed wording pending full-text audit — flagged in module
2018-12 · checked 2026-08-23 · verified-summary
Open source ↗
Landing page; dose specifics via Consolidated 2025 chapter + provider guide (oxytocin 10 IU IM/IV)
· checked 2026-10-17 · verified-live
Open source ↗
Earlier PPH treatment trigger: ≥300 mL with abnormal vital signs in addition to the traditional 500 mL threshold; avoid waiting for 1000 mL after caesarean before treating compromise.
· checked 2026-10-18 · verified-live
Open source ↗
4Ts assessment, atonic-PPH oxytocin, additional uterotonic choice, compression, source control, tamponade and urgent surgical escalation. WHO 2025 supplies the newer treatment-recognition trigger. Additional admission/discharge check 18 October 2026 (limited to the following): Haemorrhage resuscitat…
2023-09-29 · updated 2026-06-09 · checked 2026-08-23 · verified-live
Open source ↗
NICE overview + Update information page (dates above confirmed)
· checked 2026-10-17 · verified-live
Open source ↗
PPH treatment 5–10 IU slow IV with 20 IU/L over 2 hours, total 60 IU ceiling; separate from prophylaxis and augmentation. Pump rates in the app are explicitly calculated.
· checked 2026-10-17 · verified-live
Open source ↗
0.2 mg/mL, IM 0.2 mg repeat at 2–4-hour intervals, IV and hypertension precautions, and breastfeeding interruption in the label. No unsupported cumulative maximum added.
· checked 2026-10-17 · verified-live
Open source ↗
200–500 micrograms IM; severe-haemorrhage slow-IV 250–500 micrograms, optional dilution to 5 mL, and vascular/hypertension contraindications. Ergometrine distinguished from methylergometrine.
· checked 2026-10-17 · verified-live
Open source ↗
Refractory postpartum bleeding section: 250 micrograms/mL, 250 micrograms deep IM, 15–90-minute repeat intervals and 2 mg/eight-dose maximum; distinguished from the abortion section.
· checked 2026-10-17 · verified-live
Open source ↗
800-microgram SL PPH rescue dose, tablet strengths, route-specific labour-induction intervals and oxytocin separation.
· checked 2026-10-18 · verified-live
Open source ↗
Maternal/newborn transfer assessment, first void and effective feeding, handover, support/safeguarding, first midwife visit within 36 hours after transfer, postnatal danger symptoms. Full recommendations page read.
· checked 2026-10-18 · verified-live
Open source ↗
Normal-delivery discharge not less than 48 hours: full primary SOP PDF normal-delivery/discharge passages read. Corroborated by NHM CEmONC 2024 Part 1, chapter 8. This does not define a universal post-caesarean or complicated-case stay.
· checked 2026-10-18 · verified-live
Open source ↗
Official WHO summary read: at least 24-hour facility care after birth; additional contacts at 48–72 hours, 7–14 days and week 6; individual assessment/support. Summary facts only, not a claim that the full 242-page PDF was reviewed.
· checked 2026-10-17 · verified-summary
Open source ↗
Recommendation A.2.1: prevention 30–60 mg elemental iron plus 400 micrograms folic acid daily; anaemia treatment 120 mg elemental iron with 400 micrograms folic acid until Hb normal, then prevention. Limited dose-scope check through the primary WHO text indexed by NCBI; not a revalidation of every 2…
· checked 2026-10-18 · verified-summary
Open source ↗
Primary recommendation table indexed at NCBI Bookshelf checked: postpartum diagnosed anaemia 120 mg elemental iron plus 400 micrograms folic acid daily until Hb normal; preventive 6–12 weeks is a separate indication. Direct table retrieval presented a browser check, so this is a limited primary-text…
· checked 2026-10-18 · verified-live
Open source ↗
Full primary patient recovery page read: pain control, wounds, activity/VTE, urinary/bowel and infection warning signs, adult support and no driving/important decisions during the first 24 hours after general anaesthesia. Used as general recovery/handover principles, not operation-specific discharge…
· checked 2026-10-18 · verified-live
Open source ↗
Full primary recommendations read, focusing on critical-care-to-ward transfer: structured written handover, shared plan, monitoring, rehabilitation and receiving-team capability. Step-down is distinct from home discharge; no universal organ-support discharge cutoff is asserted.